The 1991 Jonathan Demme classic “The Silence of the Lambs” was filmed primarily in Western Pennsylvania, with some additional scenes shot in West Virginia, Virginia and The Bahamas.

Catherine gets abducted by Buffalo Bill at this apartment complex in Pittsburgh. There was some construction going on during our visit, so we didn’t venture onto the property.

LOCATION: 1767 Crafton Blvd, Pittsburgh, PA 15205

Clarice meets some entomologists at Carnegie Museum & Library, which is only seen from interior views in the film. The same building appears in the films “Flashdance” and “Pretty Woman.”

LOCATION: 4400 Forbes Ave, Pittsburgh, PA 15213

Moxley’s Drugs can be found in the town of Homestead.

LOCATION: 200 E 8th Ave, Homestead, PA 15120

Late in the film, the FBI raids this home.

LOCATION: 1206 Lindbergh Ave, Pittsburgh, PA 15223

While the climax to the film is set in Ohio, the home of Buffalo Bill can actually be found in the rural town of Perryopolis, Pennsylvania. You can follow the Youghiogheny River up to the railroad tracks (which are in active use), into a head-on view of the famous house where Clarice Starling faced off with Buffalo Bill. The home is now open to fans as a private rental and for tours. Some mapping systems have a terrible time finding this house, so we’ve included GPS coordinates as well.

LOCATION: 8 Circle St, Perryopolis, PA 15473 (GPS coordinates: 40.090366, -79.721970)

Just across the tracks, you can still see the same RV that was seen in the establishing shot of the house.

The exterior of the Baltimore State Forensic Hospital where Hannibal Lector is imprisoned was actually filmed at 333 Curry Hill Rd, Canonsburg, PA 15317, but the building was demolished in 2012.

The interior scenes were filmed inside the Old Allegheny County Jail.

LOCATION: 950 Second Avenue, Pittsburgh, PA 15219

A replica of Hannibal Lector’s cell was built in the basement of the Hollywood Museum in Hollywood, California.  While not an exact match to the film, it’s pretty close.

The guard desk.

The entrance to the cell block.

The hallway.  “Stay to the right.”

Multiple Miggs’ cell.

Hannibal Lector’s cell.

LOCATION: Hollywood Museum, 1660 Highland Ave, Los Angeles, CA 90028

Related articles: Red Dragon (2002)